Trisodium Phosphate or sodium phosphate is a compound of the elements sodium and phosphate counterion. It is often found in dental products due to its enamel-restoring qualities, and it is sometimes used in medicine as a laxative. Sometimes Trisodium Phosphate is added to toothpastes in combination with other ingredients to prevent cavities and to restore lost enamel, but it can also be purchased separately as a tooth cleanser and protectant.

Most times, Trisodium Phosphate comes in crystals and powdered form. It is colorless and odorless. When used for oral health purposes, it is generally dissolved in water with one part Sodium Phosphate to four and a half parts water. This combination can be applied directly to the teeth to restore enamel and prevent disease of the teeth and gums. In some cases it is also an ingredient in toothpaste and mouthwash.